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The largest participative network on microencapsulation

3th Latin-America Symposium on Microencapsulation

Pucon, Chile
November 27-29, 2017

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21th Microencapsulation Industrial Convention

Montreal, Canada
May 21-24, 2018

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10th Training School on Microencapsulation

Throndheim, Norway
September 2018

More information, available in January

Microencapsulation News

 

2018-02-22
Thesis
Publ. : 22 NOV. 2017 - Deadline : 22 FEB. 2018
Beta-lactoglobulin and lactoferrin complex coacervates for the encapsulation of a model bioactive, the vitamin B9?

Date : 26 of October 2017 Place : Laboratoire Sciences et Technologie du Lait de l'Oeuf, Agrocampus Ouest, Rennes, France Functional foods are a s bject of growing interest today, motivated by their potential to prevent diseases and contribute to healthier daily lifestyles. Encapsulation of bioactives represents a great potential for the development of such products, with enhanced health benefits. Given the food industry’s desire to develop and promote a “clean label”, the use of food proteins as encapsulating agents appears to be relevant. In parallel, whey proteins (WP), co-products of the dairy industry, exhibit good potentialities for use as encapsulating agents that could in fine enhance their functional and economic value. Moreover, previous works have demonstrated that the two WPs, beta-lactoglobulin (BLG) and lactoferrin (LF), are able to spontaneously co-assemble by complex coacervation, a known encapsulation technology. In that context, this study aims to explore BLG and LF complex coacervation for the encapsulation of a model bioactive, vitamin B9. A series of experiments have made it possible to establish the domains of B9-LF-BLG coacervation according to a tested range of pH, proteins and vitamin molar ratios. In our study, optimal conditions for B9-WP coacervation were found in water, at pH 5.5, with a LF:B9:BLG molar ratio of 1:5:10, to obtain WP coacervation yields of between 45 to 55% and B9 encapsulation up to 98%. WP complex coacervation was then scaled-up from the laboratory to the bench scale using commercial-grade protein solutions and static mixing. Final efficiencies, similar to the laboratory scale, were reached, allowing the production of B9-WP coacervates containing 4 mg of B9/g WP coacervates. Under degradative conditions in vitro (UV light irradiation, oxidation by H2O2, freeze-drying), WP coacervates demonstrated good protective properties to limit chemical degradations of B9. Moreover, in vivo oral administration of B9-WP coacervates in rats made it possible to enhance the plasmatic concentrations of the vitamin compared to oral administration of unencapsulated B9. B9-WP coacervates also showed good physical stability over time when incorporated into milk in the form of small droplets suspended in solution. The combined results of this thesis provide a better insight into heteroprotein complex coacervation, attempting to link the theory behind this long-established chemical concept to its potential interest for innovative applications.

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2018-05-21
Industrial Convention
Publ. : 06 NOV. 2017 - Deadline : 21 MAY 2018
21st Microencapsulation Industrial Convention - Montreal, Canada - May 21-24, 2018

We are please to invite you to register for the next 21st Microencapsulation Industrial Convention. A combination of expert presentations, exhibitions and a business to business trade fair (hundreds of individual meetings). Register soon to get low registration fees and get an exceptional accommodation rate at the 4 starts convention hotel.

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2018-09-30
Training School
Publ. : 06 NOV. 2017 - Deadline : 30 SEPT. 2018
10TH training school on microencapsulation - Throndheim, Norway - September 2018

The 10TH training school on microencapsulation will focuse on heath applications of microencapsulation. It will be held in Throndheim, Norway in Septe ber 2018. The web site will be open in January 2018

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2018-08-27
conference
Publ. : 02 OCT. 2017 - Deadline : 27 AUG. 2018
BIOBARRIERS 2018 - 27 – 29 August 2018 in Saarbrücken, Germany

The 12th International Conference and Workshop on Biological Barriers is an international scientific event, organized every two years and receiving co stantly 200+ registered attendees from all over the world. In the focus of BioBarriers 2018 are human cell and tissue models for facilitating clinical translation of new drugs and delivery systems, especially in the context of infectious diseases. Moreover, we will discuss innovative concepts and materials, also capable to overcome non-cellular diffusion barriers such as mucus or bacterial biofilms, concluding the conference with sessions on extracellular vesicles and advanced nanomedicines for non-invasive delivery of macromolecular biopharmaceuticals. Target audiences are early stage researchers as well as experienced scientists and professionals from academia and the pharmaceutical industry.

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